For clinical applications, analytical pathology is an important and basic research field in understanding the behavior of diseases. Pathomorphological methods can be used to examine pathological changes in organs, tissues, or cells of the body. In order to explore the disease process of organs, tissues, or cells, we can use some pathomorphological examination method to examine their diseases, discuss the causes, pathogenesis, occurrence and development process of diseases, and finally make pathological diagnosis. For instance, pathological examination of the tumor is one of the most important methods of tumor diagnosis. Pathology can determine the diagnosis, tissue origin, nature and scope of tumors, and provide important basis for clinical treatment.

In vivo pathological analysis uses scanning techniques with mathematical analysis tools (i.e. computer and AI). The in vivo techniques involve ultrasound and nuclear magnetic resonance scanning, ultrasound imaging (USG) and gamma γ-scintigraphy, X-ray computed tomography (X-ray CT or CT), magnetic resonance imaging (MRI) and emitter tomography, single photon emission tomography (SPECT) and positron emission tomography (PET), and other new imaging technologies. The advanced in vitro pathological analysis includes histochemistry, immunohistochemistry, molecular biology and oncogene examination. With the rapid development of natural science, new instruments and technologies are applied to medicine. New methods such as ultrastructure pathology, molecular pathology, immunopathology and genetic pathology have been also applied to pathological examination.

In short, in vivo and in vitro pathological analysis at cellular and molecular levels is important for all clinical applications. The aim of this Special Issue is to invite the submission of original research and review articles focusing on various topics related to in vivo and in vitro pathological analysis at cellular and molecular levels for clinical applications.

Potential topics include but are not limited to the following:

1. In vivo study
2. In vitro study
3. Pathological analysis at cellular level
4. Pathological analysis at molecular level
5. Smart biomedical devices and equipment
6. Medical treatment and nursing
7. Scanning techniques
8. Mathematical models for biomedical analysis
9. Artificial intelligent and deep learning
10. Investigation, acquisition, and analysis of biomedical data

Original Research Articles, Reviews, Systematic Reviews, Mini Reviews, Brief Research Reports, and Commentaries are welcome, but due to the scope of this Special Issue, please observe that Case Reports and Hypothesis & Theory articles are not to be submitted here and shall be directed to the journal's regular submissions portal.

For authors, please also review the journal's information regarding Author Guidelines and Article Processing Charges, or direct any questions to the Editorial Office: por@por-journal.com.

Manuscript Deadline: 6 August 2022